The Oddball Couple features the misadventures of a dog named Fleabag and cat named Spiffy, who live together under the same roof. Spiffy is a orderly and polite cat who is a stickler for cleanliness and organization, and Fleabag is rude, obnoxious, lazy, untidy and very disorganized. Their disparate personalities are reflected in their house – which is one-half mansion and one-half dilapidated shack – and even in their car, which is half-pristine and half-junker. They have a secretary named Goldie Hound (a play on the name Goldie Hawn) who works in the office they share. The show consists of two segments lasting ten minutes each.
In the original Odd Couple series, Felix the neatnik was a photographer and Oscar the slob was a sportswriter. In this series, Spiffy the neatnik is a writer and Fleabag the slob is a photographer.