Sister, Sister is an American television sitcom starring identical twins Tia and Tamera Mowry. It premiered on April 1, 1994, and concluded after airing six seasons on May 23, 1999. The premise of the show was that the girls (playing characters Tia Landry and Tamera Campbell) were separated and adopted at birth. One was adopted by a single mother while the other was adopted by a couple, although the mother died a short time later. The two accidentally found each other fourteen years later and reunited.